Table 1.
Subject characteristics.
Table 2.
Changes in heart rate and subjective fatigue during the exercise trial.
Figure 1.
Microarray analysis of circulating miRNAs following acute resistance exercise.
(A) Accuracy of hybridization of miRNA microarray. The levels of very few miRNAs changed by >1.5-fold change at any time. (B) Self-organization map clusters generated using the 843 regulated expression profiles. We specified eight clusters and an algorithm grouped them into discrete clusters. Expression profiles were determined at before, 60 min after (Post 1h), one day after (Post 1d), and three days after exercise (Post 3d), and are designated by black dots from left to right, where Pre is set as 0 in the log2 ratio between control samples. The thick and thin lines represent the mean expression level and standard deviation, respectively.
Figure 2.
Changes in circulating miRNA levels following acute resistance exercise.
The miR-149* level had increased significantly three days after resistance exercise. miR-146a and miR-221 levels had decreased significantly five days after resistance exercise. Levels of the other miRNAs did not change significantly. *P<0.05, **P<0.01.
Figure 3.
Correlations between circulating miRNA levels and resistance-exercise-related blood parameters following acute resistance exercise.
(A) Adrenaline and noradrenaline levels correlated weakly but significantly with miR-21 levels, yielding correlation coefficients of 0.491 and 0.455, respectively; (B) miR-222 levels correlated weakly with IGF-1 and free testosterone levels, yielding correlation coefficients of 0.488 and 0.477, respectively. NA, noradrenaline.
Table 3.
Correlations between changes in miRNAs and resistance-exercise-related blood parameters.