Table 1.
Effects of family history of T2DM (FH+/−) on anthropometric and body composition variables.
Table 2.
Anthropometry, body composition, Frame and Adiposity factor scores by gender and age tertile. Mean ± SD.
Figure 1.
Loading pattern of log-transformed body size and composition variables on the ‘Frame’ and ‘Adiposity’ factors.
The loadings are the correlation coefficients between the input variables and the extracted factors.
Figure 2.
Distributions of gender- and age-adjusted body composition variables.
A–D: FH+; E–H: FH−; I–L: relative risks of occurrence (with 95%CI) in each decile of the distributions of body composition variables (FH+/FH−) The dotted line in panel A represents the fit to a bimodal normal distribution.
Figure 3.
Quantile boxplots representing the median, interquartile range and 95% confidence limits of the parameters of the bimodal distribution model obtained from the Adiposity data in FH+ by bootstrap re-sampling.
m1 = mean of the lower mode; d2 = difference between the means of the 2 modes; s = common standard deviation; α = the fraction of individuals in the higher distribution. The open circles are the estimates from the original data.
Table 3.
Phenotypic proportions (α) and estimated risk allele frequencies (q) in FH−, FH+ and unobserved T2DM-affected family members under a dominant model of inheritance of Adiposity.