Table 1.
Primer sequences used for qRT-PCR analysis of selected genes in hamsters.
Table 2.
Polyphenol, flavonoid and antioxidant activities of the ethanol extract of T. indica fruit pulp.
Figure 1.
Chromatogram of T. indica fruit pulp analysed by HPLC.
HPLC analysis was carried out on the hydrolysed sample of T. indica fruit pulp using a reversed-phase column (NovaPak C18, 150 x 3.0 mm, inner diameter 4 µm). Separation of polyphenols was achieved using a linear gradient system comprising of acetonitrile in trifluoroacetic acid (pH2.6) as the mobile phase. Absorbance was measured at 260 nm.
Table 3.
Food consumption, body weight and liver weight of control and hamsters treated with T. indica fruit pulp extracts, in the presence or absence of cholesterol.
Table 4.
Analyses of biochemical parameters of control and hamsters treated with T. indica fruit pulp extracts, in the presence or absence of cholesterol.
Table 5.
Serum antioxidant enzymes, antioxidant activities and lipid peroxidation in control and hamsters treated with T. indica fruit pulp extracts, in the presence or absence of cholesterol.
Table 6.
Hepatic antioxidant enzymes, antioxidant activities and lipid peroxidation in control and hamsters treated with T. indica fruit pulp extracts, in the presence or absence of cholesterol.
Figure 2.
The effect of ethanolic extract of T. indica fruit pulp on the expression of selected hepatic genes in hamster (n = 3).
Each bar represents mean ± standard error of mean. Values not sharing a common superscript letter differ significantly at p<0.05. Group I: standard chow plus distilled water (5 ml/kg); Group II: standard chow plus 500 mg/kg T. indica fruit pulp extract; Group III: high-cholesterol diet plus distilled water (5 ml/kg). Group IV: high-cholesterol diet plus 500 mg/kg T. indica fruit pulp extract.