Figure 1.
Volumes of interests and a three-dimensional view of the brain in MaZda.
Image slices from a T1-weighted 3D image package illustrating the volumes of interest in a 19 year old female patient. There is no focal pathology or atrophy visible. VOIs are placed bilaterally in the thalamus, hippocampi, amygdalae, caudate nuclei and putamen.
Table 1.
Texture features used in the study.
Table 2.
Texture features that differed most between the patients with EPM1 and healthy controls.
Figure 2.
Illustrative images from a 34 year old male patient with EPM1.
A) T1-weighted, B) T2-weighted and C) Fluid-Attenuated Inversion Recovery (FLAIR) MR images. Mild frontoparietal cortical atrophy can be suspected but there are no visible focal abnormalities.
Table 3.
Demographic data of 16 EPM1 patients.
Table 4.
Volumes of interest (VOI) with number and percentages of statistically significantly different texture parameters from a total of 223 texture parameters between EPM1 patients and healthy controls.
Table 5.
The number of differing co-occurence based texture parameters (p<0.05) between EPM1 patients and healthy controls in the thalamus and putamen in three distances in all five evaluated directions (maximal number = 15 parameters).
Table 6.
The directions of differing run-length-based texture parameters (p<0.05) between EPM1 patients and healthy controls in the thalamus and putamen.