Figure 1.
ADC, ASL perfusion (CBF), DSC perfusion (Tmax >5 s), and follow-up FLAIR imaging of the representative patients.
(A) A 60-year-old man underwent MRI at 8.8 hours after stroke onset. The ADC imaging showed an acute infarct in the left MCA territory. Larger perfusion defect areas were seen in the ASL map (arrow) and Tmax map (arrowhead), indicating a mismatch. The follow-up FLAIR imaging showed a progressed infarct with hemorrhage. (B) A 77-year-old man underwent MRI at 8.2 hours after stroke onset. The ADC imaging showed an infarct in the right MCA territory. Although a large perfusion defect was observed in the ASL map (arrow), the Tmax map showed only a small defect (arrowhead), consistent with the ADC and follow-up FLAIR imaging.
Figure 2.
ADC, ASL perfusion (CBF), DSC perfusion (Tmax >5 s), and follow-up FLAIR imaging of the representative patients.
(A) A 76-year-old man underwent MRI at 5.0 hours after stroke onset. An acute infarct was noted in the right centrum semiovale in the ADC and follow-up FLAIR images. A perfusion defect was observed in the ASL map (arrow) but not in the Tmax map. (B) A 60-year-old man underwent MRI at 22.6 hours after stroke onset. The ADC image showed an acute infarct in the left centrum semiovale with a corresponding perfusion defect in the ASL map (arrow), but not in the Tmax map.
Table 1.
Demographic data of clinical information and perfusion analysis (Mean±SD).
Figure 3.
The mean lesion volumes of ADC, ASL CBF, DSC Tmax(>4–6 s), and final infarct in 31 patients with follow-up image.
Bars indicate as mean±standard error. *: Statistically significant, p<0.05, by repeated measures ANOVA & LSD post hoc test.
Figure 4.
ASL and DSC lesion volumes with correlation to the final infarct volumes.
Compared to DSC, ASL usually overestimated the perfusion deficits, especially in patients with small final infarcts.