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Figure 1.

Flowchart of study design.

A total of 2433 patients met the enrollment criteria. The population were first divided into 2×3 subgroups by BMI levels and weight loss status, and analyzed in the multiple-adjusted Cox model. Stratified analysis by BMI levels was further conducted to determine the impact of high weight loss during treatment for NPC patients with different BMI levels. Footnote: d, death; n, number of patients.

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Figure 1 Expand

Table 1.

Baseline characteristics by weight loss status in patients with nasopharyngeal carcinoma (n = 2433).

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Table 2.

Unadjusted analysis for 5-year OS, DSS, LRFS, and DMFS rates.

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Figure 2.

OS for NPC patients after radical radiotherapy in 2×3 grouping by BMI levels and weight loss status.

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Table 3.

Multiple-adjusted analysis for OS and DSS among the whole population (n = 2433).

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Figure 3.

Adjusted hazard ratios of high weight loss for survival in patients stratified by BMI levels.

Hazard ratios of high weight loss for overall survival (OS) and disease-specific survival (DSS) in NPC patients receiving radical radiotherapy, stratified by BMI levels. HR was adjusted for age, sex, UICC T stage, UICC N stage, and treatment; 95% CIs were shown.

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Figure 3 Expand

Table 4.

Outcomes according to weight loss stratified by BMI levels in multiple-adjusted Cox model adjusted for age, sex, UICC T stage, UICC N stage, and treatment.

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Table 4 Expand