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Table 1.

List of the anatomical regions of interest.

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Table 2.

Summary of most dominant hubs and hub identification measures in each frequency band.

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Figure 1.

Hubs with high degree.

Hubs based on the aggregated ranking percent of each node across 88 participants and their topological maps projected into a cortical surface at the theta (A and B), alpha (C and D), beta (E and F), and gamma (G and H) bands obtained from Dnodal estimation. The ranked distribution of aggregated ranking percent included only nonzero percent nodes, and the numbers in the topological maps denote the top 5 hub locations. Abbreviated notations for each node can be found in Table 1, and ‘_L’ and ‘_R’ denote the left and right hemisphere, respectively, at each node. The horizontal axes in A, C, E, and G indicate percentage (%).

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Figure 2.

Hubs with high efficiency.

Hubs based on the aggregated ranking percent of each node across 88 participants and their topological maps projected into a cortical surface at the theta (A and B), alpha (C and D), beta (E and F), and gamma (G and H) bands obtained from Enodal estimation. The ranked distribution of aggregated ranking percent included only nonzero percent nodes, and the numbers in the topological maps denote the top 5 hub locations. Abbreviated notations for each node can be found in Table 1, and ‘_L’ and ‘_R’ denote the left and right hemispheres, respectively, at each node. The horizontal axes in A, C, E, and G indicate percentage (%).

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Figure 2 Expand

Figure 3.

Hubs with high centrality.

Hubs based on the aggregated ranking percent of each node across 88 participants and their topological maps projected into a cortical surface at the theta (A and B), alpha (C and D), beta (E and F), and gamma (G and H) bands obtained from normBC estimation. The ranked distribution of aggregated ranking percent included only nonzero percent nodes, and the numbers in the topological maps denote the top 5 hub locations. Abbreviated notations of each node can be found in Table 1, and ‘_L’ and ‘_R’ denote the left and right hemispheres, respectively, at each node. The horizontal axes in A, C, E, and G indicate percentage (%).

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Figure 3 Expand

Figure 4.

Functional cartography of a subject using the within-module z score and participation coefficient (PC) of each node, and hubs with high degree and centrality derived from modular structure.

Seven hubs were characterized as connector hubs (red box) in this subject. Nodes were classified as hubs according to z-P cartography for all subjects (A). Because all subjects presented hubs, Figure 4B displays the number of subjects who had hubs (first bar and figure) and the number of subjects who had each predominant hub depending on frequency bands (second bar and figure). Hubs were characterized in 71, 49, 78, and 80 of 88 subjects depending on frequency bands, and among them, 40, 19, 32, and 41 subjects demonstrated each predominant hub at each frequency band. Hubs based on the aggregated ranking percent of each node across 88 participants and their topological maps projected into a cortical surface at the theta (C and D), alpha (E and F), beta (G and H), and gamma (I and J) bands obtained from the modularity-based hub identification method are shown. The ranked distribution of the aggregated ranking percent included only nonzero percent nodes, and the numbers in the topological maps denote the top 5 hub locations. Abbreviated notations for each node can be found in Table 1, and ‘_L’ and ‘_R’ denote the left and right hemispheres, respectively, at each node. The horizontal axes in A, C, E, and G indicate percentage (%), not corrected by the number of subjects who had hubs in Figure 4B.

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Figure 5.

Ranked distribution of Dnodal (A, B), Enodal (C, D), normBC (E, F), and z-P (G, H).

Shown are the top 20 hubs based on the aggregated ranking percent of each node across 88 participants and their topological maps projected into a cortical surface derived from Dnodal (A and B), Enodal (C and D), normBC (E and F), and z-P (G and H) measures irrespective of frequency bands. The most consistent hubs, F1, T2P, MCIN, and PCIN, are marked in each topological map. Horizontal axes in A, C, E, and G indicate percentage (%). The size of the filled circles is proportional to the corresponding percent, and the color indicates each frequency band (Theta: red, alpha: green, beta: yellow, gamma: blue).

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