Table 1.
Demographic and clinical parameters in study subjects.
Table 2.
Univariate linear regression analyses for fasting GLP-1 level and AUCGLP-1.
Table 3.
Multiple linear regression analysis for AUCGLP-1 and independent variables.
Figure 1.
Relationship between blood pressure and AUCGLP-1.
AUCGLP-1 was weakly correlated with SBP (r = −0.26, p = 0.0085, Panel A). However, a significant correlation was not observed for the AUCGLP-1– DBP relationship (Panel B). SBP, systolic blood pressure; DBP, diastolic blood pressure; AUCGLP-1, area under the curve of GLP-1 level in the oral glucose tolerance test.
Table 4.
Multiple linear regression analysis for SBP and independent variables.
Table 5.
Multiple linear regression analysis for DBP and independent variables.
Figure 2.
Blood pressure - AUCGLP-1 relationships in the high and low AUCGLP-1 groups.
In the high AUCGLP-1 group, neither SBP nor DBP correlated with AUCGLP-1 (Panels A and B). In contrast, there were significant correlations between AUCGLP-1 and SBP (r = −0.40, p = 0.0032, Panel C) and between AUCGLP-1 and DBP (r = −0.28 p = 0.0448, Panel D) in the low AUCGLP-1 group. SBP, systolic blood pressure; DBP, diastolic blood pressure; AUCGLP-1, area under the curve of GLP-1 level in the oral glucose tolerance test.
Table 6.
Demographic and clinical parameters in low AUCGLP-1 group and high AUCGLP-1 group.
Figure 3.
Time courses of PG and IRI in the OGTT.
Broken lines and solid lines indicate the low AUCGLP-1 group and high AUCGLP-1 group, respectively. The low AUCGLP-1 group showed significantly higher PG level at 60 min after glucose loading than in the high AUCGLP-1 group (Panel A). *p = 0.039. There was no inter-group difference in time courses of plasma IRI during the OGTT (Panel B). PG, plasma glucose; IRI, immunoreactive insulin.