Figure 1.
Representative MRI of patients with radiation-induced temporal lobe necrosis.
(a) the T2-weighted axial image shows a finger-like lesion of increased signal intensity (between the arrows); (b) the post-contrast T1-weighted axial image shows a lesion with necrosis and heterogeneous signal abnormalities (between the arrows); (c) the T2-weighted axial image shows an oval cyst with high T2 signal intensity (between the arrows).
Figure 2.
Kaplan-Meier curve of temporal lobe necrosis probability.
Comparison of patients treated with intensity-modulated radiotherapy (IMRT) or conventional two-dimensional radiotherapy (2D-CRT).
Table 1.
Characteristics of the study population treated by 2D-CRT and IMRT.
Figure 3.
Latency of occurrence of temporal lobe necrosis.
Patients treated with intensity-modulated radiotherapy (IMRT, left) vs. two-dimensional conventional radiotherapy (2D-CRT, right). Standard error bars are included and the thick horizontal line for each set of data points represents the median latent period.
Table 2.
Multiple comparison results of TLI latency between patients with different T classifications.
Figure 4.
Kaplan-Meier curves comparing the probability of temporal lobe necrosis in T1-T4 patients.
T1 disease (A), T2 disease (B), T3 disease (C), T4 disease (D) treated with intensity-modulated radiotherapy (IMRT) or two-dimensional conventional radiotherapy (2D-CRT).