Table 1.
Demographic and clinical features of the autistic children group.
Figure 1.
Scatter plot showing oxidative stress markers in urine and plasma and antioxidant enzymes activities in erythrocytes.
Au = Autistic children; TD = typically developing children. Horizontal bars indicate means. Standard deviation values and whether parametric or not parametric statistic tests were applied, are reported in Tab. 2. p<0.01 highly significant; p<0.05 significant; ns, not significant.
Table 2.
Erythrocyte membrane features and molecules, oxidative stress markers in urine and plasma, antioxidant enzymes activities in erythrocytes.
Figure 2.
Scatter plot showing erythrocyte membrane features and molecules.
Au = Autistic children; TD = typically developing children. TMA-DPH and DPH values are inversely correlated with the outer and the inner membrane fluidity, respectively. TBARS = Thiobarbituric Acid Reactive Substances. Horizontal bars indicate means. Standard deviation values and whether parametric or not parametric statistic tests were applied, are reported in Tab. 2. p<0.01 highly significant; p<0.05 significant ns, not significant.
Table 3.
Erythrocyte membrane Fatty Acid profile.
Figure 3.
Relevant correlations between Au clinical features and biochemical data.
Au patients were divided into three levels of cognitive/developmental impairment as follows: 1: mild, 2: moderate, 3: severe. TMA-DPH values are inversely correlated with the outer membrane fluidity. SFA = Saturated Fatty Acids. CARS activity level item score denotes hyperactivity. p<0.01 highly significant; p<0.05 significant. More details are reported in Tab.4.
Table 4.
Significant correlations of clinical features and biochemical data in Autistic children.
Table 5.
Summary of published results on fatty acid composition of erythrocyte membrane.