Figure 1.
MoMHR = metal-on-metal hip resurfacing, THA = conventional hip replacement using a non-metal-on-metal bearing.
Table 1.
Patient characteristics and metal levels.
Figure 2.
Bone endpoints in MoMHR versus THA patients.
A) Mean difference in bone mineral density at various body sites, and B) differences in bone turnover markers between the patient groups. TRAP-5b = Tartrate-resistant acid phosphatase 5b, CTX-I = C-telopeptide of type I collagen, OC = osteocalcin, PINP = N-terminal propeptide of type-I procollagen, BAP = bone-specific alkaline phosphatase. Comparison is the difference in endpoint in MoMHR versus THA patients by paired t-test.
Table 2.
Cardiac endpoints.
Figure 3.
Urinary fractional excretion of cobalt and chromium versus plasma metal level in MoMHR patients.
Line represents regression slope and dotted line represents 95% confidence interval. Comparison is fractional excretion of cobalt versus fractional excretion of chromium by linear regression analysis (P<0.0001).
Table 3.
Neuropsychological and psychological endpoints.
Table 4.
Serum markers of renal, hepatic, and endocrine function and injury.