Table 1.
Body weight, liver weight, liver iron, hemoglobin, TIBC, serum iron and serum ferritin levels.
Table 2.
Total cholesterol, triacylglycerol and total bile acid levels in the liver and total cholesterol, triacylglycerol, glucose and pyruvate levels in serum.
Figure 1.
GO terms associated with the genes that were up-regulated in the iron-deficient group.
FDR-corrected P-values were defined by the modified Fisher's exact test with the Benjamini and Hochberg FDR correction. FDR-corrected P-values<0.05 are shaded in gray.
Figure 2.
GO terms associated with the genes that were down-regulated in the iron-deficient group.
FDR-corrected P-values were defined by the modified Fisher's exact test with the Benjamini and Hochberg FDR correction. FDR-corrected P-values<0.05 are shaded in gray.
Figure 3.
Venn diagrams representing the association of up-regulated genes with multiple GO terms.
The resulting complex interdependencies of categories were shared with differentially expressed genes in the case of non-anemic iron deficiency. The genes are represented as gene symbols.
Figure 4.
Venn diagrams representing the association of down-regulated genes with multiple GO terms.
The resulting complex interdependencies of categories were shared with differentially expressed genes in the case of non-anemic iron deficiency. The genes are represented as gene symbols.
Figure 5.
Expression of G6pc and Hamp in the livers of pair-fed and iron-deficient rats.
Liver sections taken from pair-fed (A, C) and iron-deficient (B, D) rats were analyzed by in situ hybridization using G6pc (A, B) and Hamp (C, D) probes. The data are representative of experiments performed using three rats from each group. Scale bar = 50 µm.
Figure 6.
List of genes with expression changes in livers of rats fed an iron-deficient diet.
White arrows: up-regulated gene expression, black arrows: down-regulated gene expression, gray arrows: no change.
Figure 7.
Potential hepatic metabolic changes due to an iron-deficient diet.
Thick arrows: up-regulated gene expression. Broken arrows: down-regulated gene expression.
Table 3.
Diet composition.