Table 1.
Types of Signatures of Selection detectable from genomic data. Ages of selection are based on estimations for human data in years, assuming a generation interval of 25 years [2].
Table 2.
Description of cattle genotypes available for analysis before (BF) and after (AF) filtering for cryptic relatedness and quality control.
Figure 1.
Manhattan plots of genome-wide meta-SS –log10(P-values) for Angus, Brown Swiss, Gyr and Nellore breeds.
Number of SNP indicated represents count of markers crossing the significance line (P<3.17×10−7). Red and blue diamonds are intragenic and intergenic top SNP on peaks, respectively.
Figure 2.
meta-SS, component tests, EHH and derived allele bifurcation for CNIH3 in Brown Swiss (A) and Nellore (B).
Vertical dashed lines and red diamonds represent the position of the intronic SNP detected as highly significant in Brown Swiss (BTA16:28478192, P = 3.82×10−12). Horizontal dashed lines mark the Bonferroni significance threshold (P<3.17×10−7).
Figure 3.
Descriptive Network of functional terms in Angus (A) and Brown Swiss (B).
Nodes (red circles) are annotated functional terms. Edges connecting nodes represent gene share, being thickness proportional to the number of genes shared between terms (i.e., the degree of gene set overlap).
Figure 4.
Protein network of human CNIH3, according to STRING 9.0 action view.
Nodes are proteins; edges and arrows indicate interaction. Blue edges: binding; green arrows: activation; pink edges: post-translational modification; yellow edges: expression.