Table 1.
The comparisons of severity rating definitions in different databases with current review.
Figure 1.
Flow chart of primary literature search.
TPLS: Taiwan Periodical Literature System; CJFT: China Journals Full-text.
Table 2.
Summary of the included primary literature and the retrieved relevant information about natural products or herbs (including CHMs).
Figure 2.
Retrieved findings of interactions between anticoagulant/antiplatelet agents and single Chinese herbal medicines.
* Natural products or herbs which were not identified in the Taiwan Herbal Pharmacopoeia, Chinese Medicinal Herbs Preparation, or Chinese Materia Medica were excluded. CHMs: Chinese herbal medicines.
Figure 3.
Documented severity ratings of interactions between distinct anticoagulant/antiplatelet agents and single Chinese herbal medicines.
The total interactions between distinct anticoagulant/antiplatelet agents and single CHMs were 306. The classification of “No interaction” meant that there is no interaction between the medication and the single CHMs, while “No item” meant that there was no available information about the single CHMs in the database. NMCD: Natural Medicines Comprehensive Database.
Table 3.
Documented interactions between anticoagulant/antiplatelet drugs and Chinese herbal medicine, a which might increase the risks of bleeding.