Table 1.
Public Rosetta servers available prior to current work, in chronological order of development.
Figure 1.
Schematic of a typical server for molecular modeling.
Figure 2.
Schematic of ROSIE (Rosetta Online Server that Includes Everyone), which permits a number of front-ends for job submission by users, a number of servers (stored in a unified database), and a number of backends to allow expansion of computational resources.
Figure 3.
Examples of re-usable features and widgets shared across ROSIE servers.
(a) Global job queue page, which can be filtered by specific application (e.g., docking). (b) Self-registration (not required). (c) Coordinate file uploader using Protein Databank format, (d) Automatic visualization of uploaded coordinate file, (e) Score vs. root mean squared deviation plotting widget, (f) Automatic rendering of final models, which can be customized by developer for specific applications (in this case, RNA de novo modeling).
Table 2.
Applications made available via the Rosetta Online Server Including Everyone (ROSIE), in chronological order of development.
Table 3.
Files required for app implementation and their role.