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Table 1.

Demographics of SVD and control groups.

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Table 2.

MRI results in SVD cases and controls.

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Figure 1.

DTI histograms of Normal Appearing WM in SVD and control groups.

Normalised frequency histograms of diffusion tensor imaging data are presented for SVD (solid lines) and control (dashed lines) groups. FA–Fractional Anisotropy; MD–Mean Diffusivity (×10−3 mm2s−1); AD–Axial Diffusivity (×10−3 mm2s−1); Radial Diffusivity (×10−3 mm2s−1). SVD–Small Vessel Disease Group. CON–Control Group.

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Table 3.

DTI Histogram Group Results.

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Table 3 Expand

Figure 2.

Cognitive Profile in the SVD Group.

Average scores for cognitive indices are presented for the SVD group. Error Bars represent +/−1 standard error of the mean. Solid line at zero represents the expected performance for a group of average ability. EF–Executive Function; PS–Processing Speed; WM–Working Memory; LTM–Long-term “episodic” memory; PIQ–Performance IQ; VIQ–Verbal IQ; GC–Global Cognition measure. ***index score significantly different from zero, p<0.001; *index score significantly different from zero, p<0.05.

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Figure 2 Expand

Table 4.

Predictors of key cognitive domains in SVD.

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Table 4 Expand