Table 1.
Percentage of absolute and relative difference in the number of fibers inter- and intra-lobe between 22q11DS and the control group and their significance.
Figure 1.
Three-dimensional representations of the virtual fibers with significant differences between patients and controls.
Inside the three-dimensional cortical view of each hemisphere in light grey, each segment of the fibers are represented with 3 canonical directional color gradients, green for anterior-posterior axis, blue for bottom-up axis and red for left-right axis. Virtual fibers have been regrouped in “Tube” shape by TrackVis Software (http://trackvis.org/). Part A represents the decrease in the left fronto-temporal connections comprising the arcuate and the uncinate fasciculus (Video S5). Part B represents the increase in the frontal lobe intra connections (Video S1) and the decrease in the left occipital intra connections (Video S8). Part C shows the increase in the right parietal intra connections (Video S2) and parieto-occipital connections (Video S3). Part D illustrates the decrease in bilateral limbic intra and inter connections (Video S4, S7 and S9) and the left parieto-limbic connections (Video S6).