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Figure 1.

The photomicrography shows a vesicular type of grain.

The hyphae are mainly in the periphery and are swollen. The centre of the grain consists of cement substance (H&E×40).

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Figure 1 Expand

Figure 2.

The photomicrography shows melanin in the grain.

The hyphae at the periphery of the grain are covered with melanin (Masson-Fontana stain for melanin ×40).

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Figure 2 Expand

Figure 3.

The photomicrography shows cements substance and hyphae staining a blue colour with Schmorl’s stain for melanin (Schmorl’s stain ×40).

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Figure 3 Expand

Figure 4.

The photomicrography shows the hyphae and cement substances are positive for calcium (Von Kossa stain ×40).

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Figure 4 Expand

Table 1.

The mean values of the heavy metals concentrations in the patients’ biopsies & the control.

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Table 1 Expand