Table 1.
Characteristics of patients in the AMH and GOERM cohorts.
Figure 1.
AMH data (dots) plotted on a logarithmic scale with smoothed mean (dashed line) similar to ref.19, and an estimate of the mean as a quadratic function of age (solid line) with upper and lower 95% confidence limits (dotted lines).
Figure 2.
Age-dependent AMH-percentiles: 5% & 95% (dotted lines), 10% & 90% (dash-dot-dash lines), 25% & 75% (dashed lines), and 50% or median (solid line), with • denoting AMH level 2.5 ng/mL at age 30 years.
Figure 3.
(a)–(f): comparisons of cumulative frequency distributions of age at menopause from the GOERM study (solid lines) and model-based predictions from AMH falling below a critical threshold (dashed lines) for different BMI categories and smoking status, showing quite good concordance between these.
a): normal weight non-smokers ; (b): normal weight current or past smokers ; (c): over-weight non-smokers ; (d): over-weight current or past smokers ; (e): obese non-smokers; (f): obese current or past smokers.
Table 2.
Estimated thresholds below which AMH predicts menopause (with 95% confidence intervals in brackets) according to smoking status and BMI categories.
Table 3.
Estimated percentiles of the probability distributions of age at menopause (± standard errors in brackets) predicted by AMH falling below critical thresholds according to smoking status and BMI categories.
Table 4.
Estimated percentiles of the probability distribution of age at menopause (± standard errors in brackets) predicted by AMH falling below a critical threshold ignoring smoking status and BMI categories.