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Figure 1.

A directed acyclic graph representing the causal relationships between adherence club participation, outcomes, baseline and time-updated covariates.

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Figure 2.

Patients included in the analysis, enrolment into clubs, and outcomes at the end of the study.

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Table 1.

Patients characteristics at study entry and crude rates of progression to death/loss to follow-up and virologic rebound by club participation.

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Table 2.

Factors associated with adherence club enrolment.

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Table 2 Expand

Figure 3.

Estimated effect of club participation from unweighted and weighted Cox models.

Weighted model with baseline covariates estimates the parameters of a marginal structural model, adjusting for confounding due to measured time-dependent covariates.

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Figure 3 Expand