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Figure 1.

Vitamin D metabolism.

1,25(OH)2D and PTH influence vitamin D metabolism by positive (+) or negative (−) regulation of the activity of the 1α-hydroxylase and the 24-hydroxylase. 25(OH)D, 25-hydroxyvitamin D; 1,25(OH)2D, 1,25-dihydroxyvitamin D; 24,25(OH)2D, 24,25-dihydroxyvitamin D; 1,24,25(OH)3D, 1,24,25-trihydroxyvitamin D.

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Figure 1 Expand

Table 1.

Patient characteristics at inclusion (n = 52).

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Table 1 Expand

Table 2.

Patients divided into tertiles according to serum levels of 25(OH)D.

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Table 2 Expand

Table 3.

Patients divided into tertiles according to serum levels of 1,25(OH)2D.

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Table 3 Expand

Table 4.

Patients divided into tertiles according to serum levels of PTH.

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Table 4 Expand

Table 5.

Selected SNPs analysed in 52 individuals with primary hyperparathyroidism.

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Table 6.

Relations between the genotype variations of the SNPs studied and bone mineral density in lumbar spine, femoral neck and distal radius.

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Table 6 Expand