Table 1.
Demographic, laboratory, and clinical characteristics of enrolled RA* patients.
Table 2.
Univariate analysis of correlations between independent markers and measures of clinical arthritic activity.
Figure 1.
Performance and correlation of DAS28-MCP-1 with DAS28.
Correlation analysis was performed by estimating Pearson’s correlation coefficients for 111 patients with rheumatoid arthritis, including 48 newly diagnosed (blood drawn four times in a 6-month period) patients and 63 patients undergoing standard treatment (blood drawn only once). (A) Overall correlation between DAS28-MCP-1 and DAS28 (48 newly diagnosed patients at 0 months plus 63 patients) (r = 0.984 and P<0.001). (B) Change in DAS28-MCP-1 during a 6-month period was assessed by ANOVA and post-hoc LSD test. The P-values were <0.001, 0.022, and <0.001 for the comparison of 0 (n = 48) months, with 1 (n = 44), 3 (n = 36), and 6 months (n = 30), respectively. Values were expressed as mean ± SD. (C) Correlation between DAS28 and DAS28-MCP-1 at 0 months among newly diagnosed patients (r = 0.944 and P<0.001). (D) Correlation between DAS28 and DAS28-MCP-1 at 1 months among newly diagnosed patients (r = 0.951 and P<0.001). (E) Correlation between DAS28 and DAS28-MCP-1 at 3 months among newly diagnosed patients (r = 0.862 and P<0.001). (F) Correlation between DAS28 and DAS28-MCP-1 at 6 months among newly diagnosed patients (r = 0.865 and P<0.001).
Table 3.
Multivariate analysis of correlations between independent markers and measures of clinical arthritic activity.
Table 4.
Multivariate analysis of correlations between independent markers and measures of clinical arthritic activity for RA patients with serum CRP<10 mg/L.
Table 5.
Multivariate analysis of correlations between independent markers and measures of clinical arthritic activity for RA patients with serum CRP≥10 mg/L.
Table 6.
Multivariate analysis of correlations between independent markers and measures of clinical arthritic activity for RA patients with blood ESR <28 mm/hr.
Table 7.
Multivariate analysis of correlations between independent markers and measures of clinical arthritic activity for RA patients with blood ESR ≥28 mm/hr.