Figure 1.
Study population (n = 34).
Table 1.
Clinical characteristics of nonfailing hearts.
Table 2.
Clinical characteristics of failing hearts.
Figure 2.
Ventricular remodeling in heart failure.
(A) Ventricular remodeling of major ion channel subunits and accessory proteins in heart failure. (B) Regional specificity of targets in failing and nonfailing hearts of both genders.
Figure 3.
Gender dependent comparison of relative expression levels of all genes.
(A) Nonfailing male versus female LA. (B) Failing male versus female LA showing a distinct male bias. (C) Nonfailing male versus female LV. (D) Failing female versus male LV. The dotted diagonal line represents equal expression levels between genders.
Figure 4.
Gender dependent remodeling in the LA.
(A) Gender dependent atrial remodeling of major ion channel subunits and accessory proteins in failing and nonfailing hearts of both genders. (B) Relative expression levels of failing LA samples of both genders. The white data points indicate the patient with a documented history of AF.
Figure 5.
Gender dependent remodeling of adrenergic receptors.
(A) Gender dependent atrial remodeling of adrenergic receptors in failing and nonfailing hearts of both genders. (B) Relative expression levels of adrenergic receptors in failing LA samples of both genders. The white data points indicate the patient with a documented history of AF.
Figure 6.
Gender dependent ventricular remodeling of major repolarizing ion channel subunits and accessory proteins in failing and nonfailing hearts of both genders.
Figure 7.
Relative expression levels of failing LV samples of both genders.
The white data points indicate patients with a documented history of ventricular tachyarrhythmias.
Figure 8.
Average ratios of epicardial to endocardial expression of repolarization targets in failing and nonfailing hearts of both genders.
The dotted back line represents a ratio of one.