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Figure 1.

Biogenesis of mature miRNAs and their functional activity.

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Figure 2.

Histogram and corresponding Poissonness plot of the sequence lengths (sizes) of human mature miRNA molecules.

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Figure 3.

Histogram of sequence lengths of human mature miRNA molecules and four fitted models.

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Figure 4.

The sample proportions of nucleotide bases and GC, AU contents.

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Figure 5.

Histograms and fitted distributions of the sequence lengths of mature conserved and human – specific miRNAs.

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Table 1.

All human mature miRNAs associated with cancer and their functions.

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Figure 6.

Distributions of the sequence lengths of human pre-miRNAs.

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Figure 7.

Scatter-plot of the average sequence length of pre-miRNAs versus the sequence length of miRNAs: the red line is the linear regression and the blue curve is the quadratic polynomial regression.

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Figure 8.

Bar charts of mature miRNAs in the 5′ and 3′ arms of the precursors respectively.

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Figure 9.

Scatter-plot of the average numbers of predicted target genes versus the mature miRNA sequence length.

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Figure 10.

Histograms of target site counts of the transcripts predicted by miRNAs with the same sequence lengths.

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