Figure 1.
The different vitamin B6 vitamers and their intracellular conversions.
PK = pyridoxal kinase. PNPO = pyridox(am)ine phosphate oxidase. PLP-Ph = PLP-phosphatase.
Figure 2.
Expression of the enzymes involved in vitamin B6 metabolism in human cell lines and tissue lysates.
Actin was used as a loading control (cell lysates only). Depicted are representations of at least duplicates. PK = pyridoxal kinase. PNPO = pyridox(am)ine phosphate oxidase. PLP-Ph = PLP-phosphatase. Small Int = small intestine. HepG2 = HepG2 cells. Caco-2 = Caco-2 cells.
Table 1.
Apical and basolateral amounts of PN, PM and PL in time during incubation with 100 and 1000 nmol/L of either B6 vitamer.
Figure 3.
Intracellular amounts of PLP during incubation with no B6 vitamers, PN, PM and PL.
Depicted are means ± SE of triplicates.
Figure 4.
Changes in apical and basolateral amounts of PL during incubation with PN (A) or PM (B).
Depicted are means ± SE of triplicates.
Figure 5.
Hypothesis of human intestinal vitamin B6 metabolism.