Figure 1.
Examples of indocyanine green angiography (ICGA) and spectral domain optical coherence tomography (SD-OCT) in highly myopic eyes.
ICGA (left) and SD-OCT (right) in highly myopic eyes without lacquer crack (top), with linear lacquer cracks (middle), or with stellate lacquer cracks (bottom). (Top). No lacquer cracks shown on ICGA and SD-OCT reveals a choroidal layer of normal thickness. (Middle). Linear lacquer cracks seen on ICGA and SD-OCT shows a mildly reduced subfoveal choroidal thickness. (Bottom). Stellate lacquer cracks seen on ICGA and SD-OCT reveals a markedly reduced subfoveal choroidal thickness compared to top right and middle right.
Figure 2.
Identification of Additional Biometrical Markers of Lacquer Cracks.
Subfoveal choroidal thickness is compared to the width of the RPE, distance between the outer layer of the RPE to the inner segment/outer segment line (RIOS), and the distance between the outer layer of the RPE to the external limiting membrane (REL), at the center of the foveola. The sensitivity, specificity, and accuracy of these relationships at predicting lacquer crack formation were calculated.
Table 1.
Types of Patients Recruited to this Prospective Study.
Table 2.
Summary of Biometrics for Eyes with and without Lacquer Cracks.
Figure 3.
Scatterplots of macular choroidal thickness vs subfoveal choroidal thickness in all eyes.
Solid circles show eyes with lacquer cracks and unfilled circles show eyes without lacquer cracks. Subfoveal choroidal thickness correlated significantly with macular choroidal thickness in all eyes (R2 = 0.919, P<0.001).
Table 3.
Comparison of Biometrics between Eyes with Linear or Stellate Lacquer Cracks.
Figure 4.
Receiver operating characteristic curves of 4 biometrics at predicting the formation of lacquer cracks.
The areas under the curve from the highest to lowest were macular choroidal thickness (0.926), subfoveal choroidal thickness (0.897), axial length (0.858), and refractive error (0.694).
Table 4.
Cutoff Values and Areas under the Receiver Operating Characteristic Curve for 4 Biometrics at Predicting Lacquer Crack Formation.
Table 5.
Comparison of the Sensitivity, Specificity, and Accuracy of the Biometrical Relationships at Predicting Lacquer Crack Formation.