Figure 1.
Process to determine number of people treated and diabetes cases prevented under each prevention strategy.
Legend: 1 In sensitivity testing, only people with an elevated BMI (BMI>25) were treated. 2 The initial high-risk strategy scenario targeted people with a 5 year diabetes risk greater than 10%. An alternative approach targeted the highest risk people, followed by people at incremental lower risk. 3 The primary scenario was the strategy scope required to prevent diabetes by 10% between 2003 and 2008.
Figure 2.
Five-year risk of diabetes by decile of risk and body mass index, Ontario, 2003.
Legend: The predicted five-year probability of diabetes (DM) calculated using the Diabetes Population Risk Tool (DPoRT) compared to the observed probability of diabetes, by (A) deciles of risk and (B) body mass index categories. The observed probability of diabetes was ascertained using the Ontario Diabetes Database individually linked to the Ontario sample of the Canadian Community Health Survey.
Table 1.
Strategy scope required to prevent diabetes by 2.5%, 10% or 20%.
Figure 3.
Incremental diabetes prevention based on scope of pharmacotherapy, lifestyle therapy, or community-wide strategy.
Legend: High-risk (A) and general (B) population coverage of pharmacotherapy or lifestyle therapy with diabetes preventive benefit equivalent to different levels of body mass index (BMI) reduction. Greater reductions of diabetes (x-axis) require either greater reductions of indivdual therapy or community-wide BMI reduction. For example, for people at high-risk of developing diabetes (A), a 10% reduction in new cases of diabetes would require indivdual therapy coverage of 65% for pharmacotherapy or 32% for lifestyle therapy. Alternatively, a community-wide 3.5% BMI reduction would achieve the same 10% reduction in diabetes.