Table 1.
Derivation of the final study population after adoption of all entry criteria.
Table 2.
Demographics and disposition of study patients following final screening.
Table 3.
Top ten primary diagnoses at visit of lumbar puncture for patients ages 20–95.
Figure 1.
Mean CSFP within specific age groups.
Bars represent one standard deviation.
Table 4.
Mean cerebrospinal fluid pressure (mm Hg) by age categories.
Table 5.
Bivariate analysis of mean cerebrospinal fluid pressure (mm Hg) as a function of BMI within specific age groups.
Figure 2.
Segmented multivariate linear regression model CSFP (mm Hg) by age and sex.
For each year of increase in age, CSFP decreased 0.009 mmHg (p = 0.132) for age <50 and by 0.056 mmHg, (p<0.001) for age greater than 50. Prior to age 50, the slope is not different between males and females (p = 0.369). After age 50, the gender difference in the slope is borderline significant (p = 0.067). The r2 of this model is 0.071.
Figure 3.
Average intraocular pressure against age.
Formula for the regression: y = −0.0144×+15.575, r2 = 0.003.
Table 6.
Intraocular pressure, cerebrospinal fluid pressure, and translaminar pressure difference by age groups.