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Table 1.

Risk factors of MRSA and matched MSSA control group isolates.

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Figure 1.

Diversity analysis of all MSSA (S1–S46) and MRSA (R1–R46) isolates by splits graph.

(A) Splits graph constructed based on cost distance matrix produced by Ridom StaphType and (B) on default settings of the IdentiBAC microarray hybridization profiles of 334 genes and alleles. Clonal complexes (CC) as well as the most abundant spa-types t003 (circles) and t012 (quadrates) were highlighted.

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Table 2.

Differences of spa-types and clonal complexes in MSSA and MRSA isolates.

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Figure 2.

Subclassification analysis of 41 MRSA (R1–R41) and two MSSA (S42, S43) of CC5.

(A) Splits graph based on cost distance matrix computed by Ridom StaphType software. (B) Splits graph based on MA hybridization profiles. Characteristic gene profiles for isolate cluster assignment were arbitrarily stated into group A-E. The most common MRSA spa-types t003 (circles), t504 (quadrates) and t010 (hexagons) were highlighed.

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Figure 3.

CC5 isolates (n = 43) characterized by spa-typing and comprehensive MA subgroup analysis using three different bioinformatic modes (principal component analyses, splits graph and cluster dendrogram).

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Figure 3 Expand

Figure 4.

Principal component cluster analysis (PCA) of 41 MRSA (R1–R41) and two MSSA (S42, S43) of CC5.

(A) Clustering of the 43 CC5 isolates by PCA as well as (B) subclustering of 30 MRSA CC5 cluster I isolates using a higher resolution PCA plot for in-depth identification of additional subgroups (Ia–Id).

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Figure 4 Expand