Table 1.
Subjects characteristics, hematological and hemorheological parameters in healthy subjects (AA) and patients with sickle cell-hemoglobin C disease (SC) or sickle cell anemia (SS).
Table 2.
Muscle force and fatigability (i.e., force decrease) in healthy subjects (AA) and patients with sickle cell-hemoglobin C disease (SC) patients or sickle cell anemia (SS).
Figure 1.
Muscle microvascular oxygen saturation (TOI) at rest in AA, SC and SS groups.
Different from AA group (*p<0.05); different from SC group (†p<0.05).
Figure 2.
Forearm blood flow at rest (2a) and muscle oxygen consumption at rest (2b) in AA, SC and SS groups.
Figure 3.
Fast Fourier Transform analysis of TOI signal variability.
Total power spectral density (3a, flowmotion activity), power spectral density in interval I, II and III (3b, vasomotion activity), power spectral density in interval IV, V (3c) and normalized spectral density (3d). Interval I = endothelial activity and/or nitric oxide metabolism, interval II = nervous sympathetic activity of the vessel wall, interval III = myogenic activity, interval IV = breathing frequency and interval V heart rate and cardiac output.
Figure 4.
Example of Fast Fourier Transform analysis of TOI signal variability in one AA subject (left), one SC patient (middle) and one SS patient (right).
The frequency axis is divided into three parts: vasomotion activity (left), interval IV (middle), and interval V (right). Note that the scale of the Y-axis is different for the three subjects.