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Figure 1.

Study design.

The bigger arrow indicates the moment of 18F-FDG injection 10 min after the beginning of exercise and the smaller arrows indicate the times of blood sampling. Trans. – transmission scanning; VO2 max – maximal oxygen consumption.

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Figure 2.

Regions of interest (ROI) drawn on MRI image example over the muscles constituting the quadriceps muscle.

RF – m. rectus femoris, VL – m. vastus lateralis, VM – m. vastus medialis, VI – m. vastus intermedius.

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Figure 3.

Representative cross-sectional PET images of glucose uptake of the thigh region during steady-state cycling with three different exercise intensities in one of the subjects.

The color scale shows the glucose uptake in a relative scale.

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Figure 4.

Glucose uptake during exercise at different exercise intensities.

Mean glucose uptake and its heterogeneity in the whole quadriceps femoris muscle group are shown in panels A and B, respectively. *p<0.05 and **p<0.01 compared to LOW.

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Figure 5.

Glucose uptake during exercise in different muscles of quadriceps femoris at different exercise intensities.

Mean glucose uptake and its heterogeneity in the four individual muscles are shown in panels A and B, respectively. RF – m. rectus femoris, VL – m. vastus lateralis, VM – m. vastus medialis, VI – m. vastus intermedius. No interaction between intensity and muscle was found in ANOVA, but both main effects (intensity and muscle) were significant and the following pair-wise differences were found: *p<0.05 and ***p<0.001 compared to LOW intensity, †p<0.05 compared to MODERATE intensity, and ‡‡p<0.01 and ‡‡‡p<0.001 compared to RF muscle. White, grey and black bars represent LOW, MODERATE and HIGH exercise intensities, respectively.

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