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Figure 1.

Decision tree for cost-effectiveness analysis of different screening strategies among all simulated live births in China.

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Table 1.

Parameter values and plausible ranges for probability variables used in baseline and sensitivity analysis.

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Table 2.

Estimation of cases detected and cases intervened by different screening strategies.

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Table 3.

Costs, health effects, and cost-effectiveness of different screening strategies.

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Figure 2.

The cost in per Disability-Adjusted Life Years (DALYs) of four screening strategies compared with no screening.

Uni.OAE+AABR = universal strategy using OAE plus AABR; Uni.OAE = universal strategy using OAE; Select.OAE+AABR = targeted strategy using OAE plus AABR; Select.OAE = targeted strategy using OAE; Reference = 3 times of GDP per capita (19,700 international dollars).

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Figure 3.

Sensitivity analysis of willingness-to-pay.

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Figure 4.

The impact of the benefit ratio on ACER of different screening strategies based on the results of sensitivity analysis.

Uni.OAE+AABR = universal strategy using OAE plus AABR; Uni.OAE = universal strategy using OAE; Select.OAE+AABR = targeted strategy using OAE plus AABR; Select.OAE = targeted strategy using OAE; ACER = Average Cost-Effectiveness Ratio.

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Figure 5.

The impact of the benefit ratio on ICER of shifting strategies based on the results of sensitivity analysis.

Uni.OAE+AABR = universal strategy using OAE plus AABR; Uni.OAE = universal strategy using OAE; Select.OAE+AABR = targeted strategy using OAE plus AABR; Select.OAE = targeted strategy using OAE; ICER = Incremental Cost-Effectiveness Ratio.

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