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Figure 1.

Flow diagram of patients registered on the UNOS liver transplant waiting list in the United States between March 1, 2002 and December 31, 2007.

Only patients with available serum sodium concentrations were included in statistical comparisons between models.

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Figure 2.

Serum albumin concentration and the risk of death within 3 months of waiting list registration after adjustment for the MELD score.

Dotted lines represent 95% confidence intervals.

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Table 1.

Characteristics of Registrants on the Liver Transplant Waiting List.

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Table 2.

C-Statistics (95% CI) of MELD and Alternative Models for Predicting Mortality on the Liver Transplant Waiting List*.

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Table 3.

Risk Reclassification Table Comparing 90-Day Mortality Risk Strata According to MELD and 5vMELD *.

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Table 4.

MELD and 5vMELD Scores among 1,113 Patients from the Validation Cohort Who Died on the Waiting List.

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Figure 3.

Difference between 5vMELD and MELD according to MELD score (< vs. ≥15) at waiting list registration and 3-month mortality.

(A) Patients who died despite low MELD scores would have had the largest increase in points had a 5vMELD-based policy been in place (P = 0.0001). (B) The proportion of patients with a difference between 5vMELD and MELD of ≥10 and ≥5 points was highest among low MELD patients who died (both P<0.0005).

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