Figure 1.
Flowchart of included studies and selection progress.
Table 1.
Characteristics of 41 included studies.
Table 2.
Definitions of exposure, outcomes, adjusted confounders, and quality score of 41 included studies.
Figure 2.
Forest plot of the association between statins and mortality for patients with infectious disease, by types of infection.
Note: Each comparison was presented by the name of the first author and the year of the publication. The studies were shown by a point estimate of the OR and the accompanying 95% CI which were displayed on a logarithmic scale using a random effects model. The studies are sorted according to the estimate of OR. Between-study heterogeneity was tested by the x2 -based Q-statistic, and its impact was quantified by I2 which can range between 0 and 100%.
Table 3.
Subgroup analyses by study design, types of infection, outcome measures and study location.
Figure 3.
Funnel plot of the association between statins and mortality for patients with infectious disease, by types of infection.