Table 1.
Characteristics of the Depressed and Control Subjects.
Table 2.
Sequences and localization on the CDS reference sequence (NCBI) of the forward (F) and reverse (R) primers used in the Q-PCR technique.
Table 3.
The mean and standard deviation (inter-individual variability) of the Ct values in the depressed and control group. The I-WV value is the mean of the inter-well Ct variation (triplicate runs).
Figure 1.
Adjustment curves of the linear regression analysis showing the direct correlation between the expression level of p16INK4 (F = 15.68, R2 = 0.51, p = 0.001) and STMN1 (F = 12.54, R2 = 0.45, p = 0.003) and the anxiety scores (HAM-A scale).
Figure 2.
Adjustment curves of the linear regression analysis showing the direct correlation of HAM-A and HAM-D scores with gene expression in the combined sample (depressed plus controls): HAM-D with p16INKa (F = 8.7, R2 = 0.27, p = 0.002), HAM-A with p16INKa (F = 21.3, R2 = 0.43, p = 0.000), HAM-D with STMN1 (F = 15.7, R2 = 0.38, p = 0.001), HAM-A with STMN1 (F = 22.8, R2 = 0.44, p = 0.000), HAM-D with TERT (F = 4.9, R2 = 0.17, p = 0.03), HAM-A with TERT (F = 9.2, R2 = 0.23, p = 0.005).
Table 4.
Correlative pattern of gene expression (Pearson's coefficient) in the blood leucocytes of controls and MDD subjects. For each gene the |r| value of control subjects (when significant) is in normal font weight on the upper row, and the |r| of the depressed patients in bold font weight on the lower row.