Table 1.
Intra- and inter-observer variability of 20 histological variables (two level classification).
Table 2.
Imaging and clinical features of EPS patients.
Table 3.
Clinical data of study patients.
Figure 1.
Histopathological findings in EPS compared to simple sclerosis.
A HE staining showing an increased cellularity, round cells and fibroblast like cells (arrows). EPS, original magnification×400; B HE staining showing a decreased cellularity, fibrin deposits and a complete denudation of the mesothelial cell layer with fibrin exudations (arrows). EPS, original magnification×100; C HE staining showing a decreased cellularity with intracellular matrix (arrows), complete mesothelial denudation with fibrin exudations. EPS, original magnification×200; D HE staining showing an increased cellularity, hemorrhage, round cells, fibroblast like cells and fibrin deposits (arrows). EPS, original magnification×400; E Fe staining showing vessels, intraluminal erythrocytes and Fe deposits (arrows). EPS, original magnification×400; F D2–40 stained section showing podoplanin positive cells associated to vessels (arrows). EPS, original magnification×400.
Figure 2.
Histopathological findings in EPS compared to simple sclerosis.
A D2–40 stained section showing podoplanin positive cells not associated to vessels (arrows). EPS, original magnification×400; B HE staining showing acute and chronic inflammation with round cells and neutrophils (arrows). EPS, original magnification×400; C HE staining showing fibroblast like cells, eosinophils, plasma cells and round cells (arrows). EPS, original magnification×400; D HE staining showing vasculitis, round cells and calcium deposits (arrows). EPS, original magnification×100.
Figure 3.
Thickness of the fibrosis zone in the submesothelial cell layer in PD patients and patients on PD with EPS.
p = 0.031; range PD group 227–2581 µm; range EPS group 281–2150 µm.
Table 4.
Frequency of histologic findings in EPS compared to simple sclerosis.
Table 5.
Classification of EPS and non-EPS cases by using random forests.