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Figure 1.

Morphological type and intralesional blood vessels in the gallbladder lesion.

Upper left, polypoid type; upper middle, thickened-wall type; upper right, mass-forming type. Lower left, scattered blood vessels; lower middle, linear blood vessels; lower right, branched blood vessels.

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Figure 1 Expand

Figure 2.

Enhancement extent of the gallbladder lesions on contrast-enhanced ultrasound.

Upper left, non-enhancing; upper right, hyper-enhancing; lower left, iso-enhancing; lower-right, hypo-enhancing (arrows indicate the lesions).

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Figure 3.

Intactness of the gallbladder wall on contrast-enhanced ultrasound.

Left, the gallbladder wall (arrow) beneath an adenoma is intact. Right, the gallbladder wall (arrow) beneath a cancer (arrowheads) is destructed and the infiltration to the adjacent liver (arrow) is observed.

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Table 1.

Basic characteristics and baseline US characteristics of the patients with gallbladder diseases.

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Table 2.

Enhancement features of the gallbladder diseases on contrast-enhanced ultrasound.

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Figure 4.

Cholesterol polyp in gallbladder.

Upper left, color flow imaging shows intralesional vascularity in the polyp (arrow); Upper right, the lesion (arrow) shows hyper-enhancement during the arterial phase; Lower left, the lesion (arrow) shows iso-enhancement during the venous phase.

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Figure 5.

Adenomyomatosis in gallbladder.

Upper left, conventional ultrasound shows a slight hypoechoic mass (arrow) in the gallbladder; Upper right, the lesion (arrow) shows inhomogeneous hyper-enhancement during the arterial phase; Lower left, the lesion (arrow) shows hypo-enhancement during the venous phase.

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Figure 6.

Adenoma in gallbladder.

Upper left, conventional ultrasound shows an isoechoic mass (calipers) in the gallbladder; Upper right, pulsatile arterial blood flow is detected in the lesion; Middle left, the lesion (arrow) shows linear blood vessels during the arterial phase; Middle right, the lesion (arrow) shows hyper-enhancement during the arterial phase; Lower left, the lesion (arrow) shows iso-enhancement during the venous phase.

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Figure 7.

Adenocarcinoma in gallbladder.

Upper left, conventional ultrasound shows an isoechoic mass (arrow) and a stone (arrowhead) in the gallbladder; Upper right, color flow imaging shows intralesional vascularity (arrow); Lower left, the lesion (arrow) shows hyper-enhancement during the arterial phase and the infiltration (arrowhead) to the adjacent liver is seen; Lower right, the lesion (arrow) shows hypo-enhancement during the venous phase and the infiltration (arrowhead) to the adjacent liver is seen.

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Table 3.

The independent variables associated with the GB benign diseases by multiple logistic regression analysis.

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Table 4.

ROC analyses of the independent variables in differentiating malignant from benign GB diseases.

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Table 5.

The advantage of CEUS measures over conventional US in the diagnosis of GB diseases.

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