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Table 1.

Characteristics of the unilateral breast cancer cohort and the CBC-cohort; 1976–2005 in the Stockholm-Gotland region.

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Figure 1.

Nelson –Aalen plots.

Cumulative incidence of CBC for women with ER-negative vs. ER-positive first breast cancer. Panel A shows the cumulative incidence of CBC of any ER-subtype by ER-status of the first cancer. The p-value for the log-rank test of cumulative incidence of CBC overall was 0.338, thus the cumulative incidence of CBC did not differ between patients with ER-positive vs. ER-negative first primary breast cancer. Panel B shows the cumulative incidence of ER-positive and ER-negative CBC by ER-status of the first cancer. (The p-value for the log-rank test of cumulative incidence of ER-positive CBC show significant difference between patients with ER-positive vs. ER-negative first breast cancer (P-value = <0.001) and similarly the p-value for the log-rank test of cumulative incidence of ER-negative CBC also show significant difference between patients with ER-positive vs. ER-negative first breast cancer (P-value = <0.001). See Table 5 for number of women at risk.

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Table 2.

Standardized incidence ratios (SIR) comparing the incidence of CBC to the incidence of unilateral breast cancer, overall and according to ER-status of the first breast cancer, for all patients and stratified on age.

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Table 2 Expand

Table 3.

Standardized incidence ratios (SIR) comparing the incidence of ER-positive and ER-negative CBC to the incidence of unilateral breast cancer, overall and according to ER-status of the first breast cancer, for all patients and stratified on age.

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Table 3 Expand

Table 4.

Standardized incidence ratios (SIR) comparing the incidence of CBC to the incidence of unilateral breast cancer, for CBC overall and for specific ER-status of first and second breast cancer, taking hormone therapy for the first cancer into account.

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Table 4 Expand

Table 5.

Number of women at risk of CBC by year after diagnosis, subdivided on ER-status of the first cancer.

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Table 5 Expand