Figure 1.
Typical PET summation images of frames between 32–60 min after intravenous injection of [11C]raclopride for baseline and drug challenge (6 mg of aripiprazole) studies.
The sections are transaxial at the level of putamen.
Table 1.
Dose of aripiprazole and ranges of occupancy of dopamine D2 receptors.
Figure 2.
Regions of interest (ROIs) drawn on coregistered MR images.
ROIs are defined for the cerebellar cortex, putamen, caudate head, and occipital cortex. Typical PET summation images of frames between 29–89 min after intravenous injection of L-[β-11C]DOPA for baseline study are also shown.
Table 2.
Dopamine synthesis capacity ki of both baseline and drug challenge studies.
Figure 3.
Relations between the occupancy of dopamine D2 receptors and the percentage change in ki by drug challenge with aripiprazole in the caudate (A) and putamen (B).
Figure 4.
Relations between ki in the baseline study and the percentage changes in ki by drug challenge with aripiprazole in the caudate (A) and putamen (B).