Table 1.
Baseline characteristics of the patients.
Figure 1.
IFN-gamma ELISpot response of peripheral blood mononuclear cells (PBMC) stimulated with a range of Mycobacterium tuberculosis antigens, expressed as IFN-gamma spot forming cells per million (SFC/106) PBMC.
TB-IRIS patients with multi-drug resistant (MDR) TB are shown in black full circles, rifampicin mono-resistant (RM) cases are shown as a cross, and fully sensitive (FS) TB cases are shown as open circles.
Table 2.
Multiplex cytokine analysis (corrected for multiple comparisons).
Figure 2.
The ratio of secreted cytokines measured by luminex analysis in the supernatants of peripheral blood mononuclear cells (PBMC) stimulated with heat killed H37Rv (MOI = 1∶1) for 24 hours.
Results from TB-IRIS patients with multi-drug resistant (MDR) TB are shown in black full circles (n = 7), rifampicin mono-resistant (RM) cases are shown as a cross (n = 3), and fully sensitive (FS) TB cases are shown as open circles (n = 10).
Table 3.
Individual patient's data on hkH37Rv stimulated release of IFN-γ, IL-2, IL-10, ratios of IFN-gamma/IL-10, IL-2/IL-10 and ELISpot responses to ESAT-6 and hkH37Rv.