Spinal connectivity analysis.
From left to right: Interspinal connectivity analysis in healthy controls (projected image), statistical comparison of controls to incomplete SCI patients (bar graph), interspinal connectivity analysis in incomplete SCI patient (projected image) and statistical comparison of controls to recovered SCI patients. The projected images represent a single subject from three angles (oblique left, coronal, obliqe right). The blue lines represent interspinal connections, the orange-yellow lines represent spinal cord-caudal brainstem connections and the red spectrum represents spinal cord-rostral brainstem connections. The number of inter-spinal connections to the prime cluster is shown as a projected image for both uninjured controls (A) and incomplete, chronic SCI patients (B). A one-way ANOVA comparing the mean number of interspinal connections to the prime cluster across healthy control (blue and red bar graph), incomplete SCI (green and purple bar graph) and recovered SCI participants (yellow and orange bar graph) was significant (p<0.001). Significant post-hoc Tukey tests included the difference between control participants stimulated in the C5 dermatome and incomplete SCI patients stimulated above the level of injury (* p = 0.045, blue vs. green bar graph) and recovered SCI participants stimulated above the level of injury (# p = 0.03, blue vs. yellow bar graph).
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