Table 1.
Study participant characteristics stratified by hormonal contraceptive use.
Table 2.
Biomarkers of glycemic control and lipid metabolism stratified by hormonal contraceptive use.
Table 3.
Plasma proteomic and C-reactive protein (CRP) analyses stratified by users and non-users of hormonal contraception in three ethnocultural groups (Whites, East Asians and South Asians/Other).
Figure 1.
Principal components analysis (PCA) in users of HC.
Four independent proteomic profiles were identified, based on a loading score criterion of >0.5. Profile 1 consisted of primarily positive acute phase reactants, while profile 2 comprised mainly negative acute phase reactants. Profile 3 consisted of complement system components and acute phase proteins, and Profile 4 represented primarily proteins involved in coagulation. * designates the 19 proteins that were significantly different between users and non-users in the whole study population. The arrows designate the direction of the difference (i.e. higher or lower levels of the protein) with respect to non-users.
Figure 2.
Principal components analysis (PCA) in non-users of HC.
In contrast to HC users, only three independent proteomic profiles were identified among non-users of HC, based on a loading score criterion of >0.5. No profile was characteristically representative of a negative or positive acute phase response. * designates the 19 proteins that were significantly different between users and nonhyphen;users in the whole study population. The arrows designate the direction of the difference (i.e. higher or lower levels of the protein) with respect to users.