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Figure 1.

Multiple views of the device.

A. The entire device, showing the rotatable arm used to change the direction of the electrode array, the angle marker, and the removable weights; B. A close-up view of the tetrapolar electrode array; C. the entire animal setup with the device overlying the gastrocnemius muscle.

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Figure 1 Expand

Figure 2.

The test-retest and Bland-Altman plots of phase at 50 kHz for healthy and ALS mice in the longitudinal configuration.

ICC values are 0.94 for healthy mice and 0.93 for ALS mice.

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Figure 2 Expand

Table 1.

Repeatability Analyses at 50 kHz.

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Table 1 Expand

Figure 3.

Major multifrequency EIM parameters (± SEM) for healthy and ALS mice in both longitudinal (0°) and transverse configurations (90°).

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Figure 3 Expand

Table 2.

Longitudinal and Transverse EIM Data in Normal and ALS Mice at Selected Frequencies.

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Table 2 Expand

Figure 4.

Normalized multifrequency anisotropy differences (± SEM) of all 3 major EIM parameters (resistance, reactance, phase) for healthy and ALS mice.

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Figure 4 Expand