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Figure 1.

Approach to selecting and categorizing patients.

EG, IG, and LG were defined as ≦ 1 day, 2–3 days, and ≧ 4 days between ICU admission and RRT initiation, respectively. Abbreviations: AKI, acute kidney injury; EG, early group; ICU, intensive care unit; IG, intermediate group; LG, late group; RRT, renal replacement therapy.

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Figure 2.

Estimated survival probability among EG, IG, and LG.

The survival period was calculated from RRT initiation. EG (blue line, n = 243), IG (green line, n = 146), and LG (red line, n = 227) were defined as RRT initiation ≦ 1 days, 2–3 days, and ≧ 4 days after ICU admission, respectively. Abbreviations: EG, early group; ICU, intensive care unit; IG, intermediate group; LG, late group; RRT, renal replacement therapy.

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Figure 3.

Probability of death by the calendar days from ICU admission to RRT initiation.

The figure was drawn using generalized additive model. Adjusted by sex, age, diabetes mellitus, chronic kidney disease, cirrhosis, extracorporeal membrane oxygenation support, initial neurological dysfunction, as well as sepsis, mean arterial pressure, inotropic equivalent, and Acute Physiology and Chronic Health Evaluation II scores at RRT initiation. Abbreviations: EG, early group; ICU, intensive care unit; IG, intermediate group; LG, late group; RRT, renal replacement therapy.

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Figure 3 Expand

Table 1.

Comparisons of demographic data and clinical parameters among the three groups.

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Table 2.

Comparisons of demographic data and clinical parameters between survivors and non-survivors.

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Table 3.

Multivariate analysis of the predictors for in-hospital mortality by fitting multiple Cox proportional hazards model with the stepwise variable selection method.

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Table 3 Expand