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Figure 1.

Flow chart of inclusion of CSF samples.

N – number of CSF samples.

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Table 1.

Age-specific reference values for CSF glucose, CSF/plasma glucose ratio and CSF lactate.

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Table 2.

Summary of literature search for reference ranges of CSF glucose, CSF/plasma glucose ratio and CSF lactate.

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Figure 2.

Age-specific CSF glucose, CSF/plasma glucose ratio and CSF lactate values.

(A) CSF glucose concentration in 8,871 samples. CSF samples with CSF glucose >10.0 mmol/L (n = 4) are not shown; (B) CSF/plasma glucose in 4,516 samples. CSF samples with CSF/plasma glucose >1.5 (n = 5) are not shown; (C) CSF lactate concentration in 7,614 samples. CSF samples with CSF lactate >5000 µmol/L (n = 22) are not shown. Lines indicate 5th and 95th percentile values.

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Figure 3.

Relation between plasma glucose and CSF glucose.

(A) Relation between plasma glucose and CSF/plasma glucose ratio in 4,508 CSF samples. CSF samples with CSF/plasma glucose ratio >1.5 (n = 5) are not shown. (B) Relation between plasma glucose and CSF glucose in 4,513 CSF samples. The grey areas indicates normoglycemia (plasma glucose >3.0 and <7.8 mmol/L).

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