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Table 1.

Patient and control details.

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Figure 1.

Analysis of neural responses to increasing social exclusion.

(A) Neural responses to increasing social exclusion in the mPFC of controls. (B) Between group differences: controls exhibited greater strength in the relationship between increasing exclusion and brain activity in the mPFC than patients. All images are thresholded at p<0.05 corrected. Bottom right: plot of the parameter estimates for increasing social exclusion averaged across voxels in a 10 mm diameter sphere centred at (6,38,−4). Error bars represent 95% confidence intervals.

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Table 2.

Within group brain activations as social exclusion increases or decreases.

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Table 3.

Group comparison in the strength of the relationship between increasing social exclusion and brain activity.

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Figure 2.

Correlation with positive symptoms in schizophrenia.

Red: controls showed significantly stronger neural responses to increasing social exclusion than patients. Green: mPFC correlation between increasing exclusion and brain activity modulated by positive symptoms. Yellow: overlap between the Red and Green regions.

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