Figure 1.
The literature search process.
Table 1.
Characteristics of the studies included in the meta-analysis.
Figure 2.
Forest plot of meta-analysis of association between CFH rs1061170 (T1277C, Y402H) and treatment response of neovascular AMD.
A, Each study is shown by the point estimate of the odds ratio (OR) (the size of the square is proportional to the weight of each study) and 95% confidence interval (CI) for the OR (extending lines). Genotype comparison: CC versus TT. B, Forest plot of meta-analysis according to treatment modality. Anti-VEGF agents indicate bevacizumab and ranibizumab; PDT, photodynamic therapy. Genotype comparison: CC versus TT.
Table 2.
Results of meta-analysis for the CFH rs1061170 (T1277C, Y402H) and treatment response of neovascular AMD.
Figure 3.
Influence analysis and publication bias plot for meta-analysis.
A shows the influence of individual studies on the summary OR (CC genotype versus TT genotype). The horizontal axis represents the odds ratio. Every circle indicates the pooled OR when the left study is omitted in this meta-analysis. The two ends of every broken line represent the respective 95% CI. B shows the Begg's funnel plot of studies included in the meta-analysis (genotype comparison: CC versus TT). The vertical axis represents ln[OR] and the horizontal axis means the standard error of ln[OR]. Horizontal line and sloping lines in funnel plot represent summary OR and expected 95% CI for a given standard error, respectively. Area of each circle represents the contribution of each study to the pooled OR.