Table 1.
A collection of deregulated lncRNAs detected using microarray in six RCCC patients.
Figure 1.
Counts of up-regulated and down-regulated lncRNAs.
Many lncRNAs were determined to be significantly up-regulated or down-regulated in RCCC samples compared with NT samples in six patients by microarray. The counts of up-regulated and down-regulated lncRNAs varied across the six patients. In four out of six RCCC patients down-regulated lncRNAs were more common than up-regulated ones. Two patient down-regulated lncRNAs were less common than up-regulated ones.
Table 2.
Summary of data from microarray for six pairs of renal cancer and adjacent normal tissues.
Figure 2.
Comparison between microarray data and qPCR result.
ENST00000456816, X91348, BC029135 and NR_024418 determined to be differentially expressed in RCCC samples compared with NT samples in six patients by microarray were validated by qPCR. The heights of the columns in the chart represent the log-transformed median fold changes (T/N) in expression across the six patients for each of the four lncRNAs validated; the bars represent standard errors. The validation results of the four lncRNAs indicated that the microarray data correlated well with the qPCR results.
Figure 3.
Distributions of the lncRNAs expression levels.
That most significantly different expressed were validated by qPCR in 63 pairs of RCCC and NT samples.