Figure 1.
Flow diagram of literature search.
Table 1.
Study characteristics of included studies.
Table 2.
Quality assessment of the included studies.
Figure 2.
Time in Therapeutic Range in individual studies.
* A weighted mean is calculated if a study reported more than 1 group; studies that only presented classes of %TTR are not represented here.
Table 3.
Percentage of time below, within and above the Therapeutic Range of the individual studies.
Table 4.
Weighted mean % of time below, within and above Therapeutic Range INR 2.0–3.0.
Figure 3.
Suggestions for calculating TTR.
Dark grey = reporting an overall TTR during treatment. Light grey = reporting the frequency of events as a function of TTR.