Table 1.
Patients’ clinical data.
Figure 1.
Correlation matrix for the full set of electrodes.
Electrodes labeled G1 through G20 belong to the lateral temporal grid; electrodes labeled S1 through S8 belong to the mesial strip. representation corresponds to a single temporal window of patient “G” (Table 1).
Figure 2.
Temporal evolution of LS for each electrode in a specific patient.
Each temporal window lasts 10.24 seconds. Representation corresponds to patient “G” (Table 1).
Figure 3.
CV for the evolution of LS throughout the recording for each electrode.
Data correspond to the activity displayed in Figure 2 corresponding to patient “G”.
Figure 4.
Localization of CV(1) to CV(5) and resected tissue in each patient (Pearson correlation coefficient).
(A) Cortical grid electrodes: Gray areas represent the approximate lateral cortical tissue resected during surgery. Superimposed, CV minima are displayed according to the key bar (right): CV(1) = 1st, CV(2) = 2nd, CV(3) = 3rd, CV(4) = 4th, and CV(5) = 5th. Patients with postoperative seizures are highlighted in blue. G1 is always at the bottom left and G20 at the top right position. (B) Mesial strip electrodes: Same schematic diagram as in panel (A).
Table 2.
Estimates, p-value and Z-scores in the four methods of synchronization between the resection of minima and seizure success.
Figure 5.
Surrogate distributions and CV(i) correlations.
(A) Density distributions of correlation coefficients for surrogate data. The upper panel corresponds to the case of a single random location. The lower panel corresponds to the case of combinations of two, three, four, and five. See text for explanation. (B) Correlation coefficient between seizure success sequence (2) and CV(i) resection, for 1 = 1, …28.
Figure 6.
LS and CV distributions. (A) Density and (B) cumulative distributions of CV for every electrode from every patient.
A lognormal distribution is superimposed (meanlog = −1.9081476, sdlog = 0.5620142). (C) Density and (D) cumulative distributions of mean LS values for all the electrode of each patient. A normal distribution is superimposed (mean = 0.5228, standard deviation = 0.1507480).
Figure 7.
(A) Three-dimensional plot showing the relations between mean (µ), deviation (σ) of LS, and CV. The first three lower CVs for each record are coloured in green. (B) Projection of the three-dimensional plot of (A) in the µ-σ plane.